General principles of tumor immunotherapy : basic and clinical applications of tumor immunology / edited by Howard L. Kaufman and Jedd D. Wolchok. - Dordrecht : Springer, c2007. - xii, 503 p. : ill. ; 25 cm.

Includes bibliographical references and index.

General principles of tumor immunology -- A perspective on cancer immunology and immunotherapy -- Tumor antigens -- T cells and antigen recognition -- The role of natural killer T cells in tumor immunity -- Immunomodulatory molecules of the immune system -- HLA class I antigen abnormalities in tumors -- The local tumor microenvironment -- Tumor vaccines -- Peptide and protein vaccines for cancer -- DNA vaccines against cancer -- Recombinant viral and bacterial vaccines -- Dendritic cell vaccines -- Whole cell vaccines -- Carbohydrate vaccines against cancer -- Passive immunotherapy approaches -- Monoclonal antibody therapy of cancer -- Adoptive cellular therapy for the treatment of cancer -- Checkpoint blockade and combinatorial immunotherapies -- Clinical tumor immunotherapy -- General approaches to measuring immune responses -- Interferon therapy -- High dose interleuken-2 therapy -- Monoclonal antibodies in cancer therapy -- Unmasking tumor cell immunogenicity by chemotherapy: implications for therapy.

9781402060861 1402060866


Neoplasms--therapy.
Neoplasms--immunology.
Immunotherapy.
Cancer Vaccines--therapeutic use.

616.994 / G3268